BENZYL BENZOATE

Fragrance Ingredient; Solvent; ANTIMICROBIAL; MASKING  

Also listed as

BENYLATE; BENZOIC ACID, BENZYL ESTER; BENZOIC ACID, PHENYLMETHYL ESTER; PHENYLMETHYL BENZOATE; BENZYL ESTER BENZOIC ACID; PHENYLMETHYL ESTER BENZOIC ACID; ASCABIN; ASCABIOL; BENYLATE; BENZOIC ACID, PHENYLMETHYL ESTER; BENZYL ALCOHOL BENZOIC ESTER


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
noCancer
noDevelopmental/reproductive toxicity
yes, moderateRestrictions & warnings
yes, moderateAllergies/immunotoxicity
noContamination concerns
noOther strong concerns for this ingredient:
Occupational hazards
noLesser or emerging concerns for this ingredient:
Endocrine disruption, Ecotoxicology, Data gaps
 
See products containing BENZYL BENZOATE

About BENZYL BENZOATE: Benzyl Benzoate is the ester of benzyl alcohol and benzoic acid.

BENZYL BENZOATE has reported used in the following product types: hair color and bleaching (116); lip gloss (109); fragrance for women (85); moisturizer (71); facial moisturizer/treatment (62); lipstick (52); anti-aging (41); styling gel/lotion (40); conditioner (34); body wash/cleanser (33)


Allergies/immunotoxicity

type of concern product conditions reference
Possible human immune system toxicant    EU Banned and Restricted Fragrances

Restrictions & warnings

type of concern product conditions reference
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)   International Fragrance Association Codes & Standards

Occupational hazards

type of concern product conditions reference
Allowed workplace exposures restricted to low doses    European Union - Classification & Labelling

Endocrine disruption

type of concern product conditions reference
Associated with endocrine disruption    Charles AK, Darbre PD, 2009

Ecotoxicology

type of concern product conditions reference
Wildlife and environmental toxicity    European Union - Classification & Labelling
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Data gaps

type of concern product conditions reference
Not assessed for safety in cosmetics by industry panel  
126 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Classified as not expected to be potentially toxic or harmful     Environment Canada Domestic Substance List
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Persistence and bioaccumulation

type of concern product conditions reference
Not suspected to be bioaccumulative     Environment Canada Domestic Substance List
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Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingBENZYL BENZOATE•Harmful
•Toxic to aquatic organisms
FDA Everything Added to FoodBENZYL BENZOATE• Fully up-to-date toxicology information has been sought.
Environment Canada Domestic Substance ListBENZOIC ACID, PHENYLMETHYL ESTER•This chemical was NOT flagged by CEPA for further attention. The chemical was flagged for as a low human health priority.
EU Banned and Restricted FragrancesBENZYL BENZOATEFragrance chemical, which is less frequently reported and thus less documented as a consumer allergen.
IFRA Fragrance Ingredient ListBENZYL BENZOATE•The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008.
International Fragrance Association Codes & StandardsBENZYL BENZOATE•Fragrance subject to restrictions: safe only within recommended use or concentration limits
Charles AK, Darbre PD, 2009BENZYL BENZOATEBenzyl benzoate demonstrated estrogenic activity by increasing the proliferation of breast cancer cells in vitro.

references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EU Banned and Restricted FragrancesSCCPNFP (Scientific Committee On Cosmetic Products And Non-Food Products). 1999. Opinion Concerning Fragrance Allergy In Consumers. . SCCNFP/0017/98 Final, December 1999; and SCCPNFP (Scientific Committee On Cosmetic Products And Non-Food Products). 2000. An Initial List Of Perfumery Materials Which Must Not Form Part Of Fragrances Compounds Used In Cosmetic Products. SCCNFP/0320/00, final May 2000.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
International Fragrance Association Codes & StandardsIFRA (International Fragrance Association). 2006. Codes and Standards.
Open scientific literatureCharles AK, Darbre PD. 2009. Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro. J Appl Toxicol. 29(5):422-34.

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