PPG-12 BUTETH-16
Fragrance Ingredient; Hair Conditioning Agent; Skin-Conditioning Agent - Miscellaneous;Solvent; Surfactant - Emulsifying Agent; PERFUMING
Also listed as
PPG-12-BUTETH-16, POLYOXYETHYLENE (16) POLYOXYPROPYLENE (12) MONOBUTYL ETHER; POLYOXYPROPYLENE (12) POLYOXYETHYLENE (16) MONOBUTYL ETHER; PPG BUTETH-600; METHYLOXIRANE, POLYMER WITH OXIRANE, MONOBUTYL ETHER; OXIRANE, METHYL, POLYMER WITH OXIRANE, MONOBUTYL ETHER; METHYLOXIRANE POLYMER WITH OXIRANE MONOBUTYL ESTER; TERGITOL NONIONIC XD; TERGITOL XD (NONIONIC) ; U-2000; U-5100; U-660
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Restrictions & warnings |
| Allergies/immunotoxicity |
 | Contamination concerns - BUTYL ALCOHOL |
 | Other strong concerns for this ingredient: Multiple, additive exposure sources |
 | Other moderate concerns for this ingredient: Organ system toxicity (non-reproductive) |
 | Lesser or emerging concerns for this ingredient: Irritation (skin, eyes, or lungs) |
|
See products containing PPG-12 BUTETH-16 | |
About PPG-12 BUTETH-16: PPG-12-Buteth-16 is the polyoxypropylene, polyoxyethylene ether of butyl alcohol thatconforms generally to the formula: where x has an average value of 12 and y has an average value of 16.
PPG-12 BUTETH-16 has reported used in the following product types: anti-fungal treatment (11); athlete's foot treatment (8); body wash/cleanser (5); anti-itch/rash cream (4); foot odor control (4); exfoliant/scrub (3); facial cleanser (2); foot cleansing (2); acne treatment (2); toners/astringents (1)
Multiple, additive exposure sources
| type of concern | product conditions | reference |
| Used in food or as an additive with limited or no toxicity information available | FDA Everything Added to Food |
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | RTECS®- Union Carbide Data Sheet 1970 |
| Classified as expected to be toxic or harmful | Environment Canada Domestic Substance List | |
| show more | ||
Irritation (skin, eyes, or lungs)
| type of concern | product conditions | reference |
| One or more animal studies show skin irritation at moderate doses | RTECS®- Union Carbide Data Sheet 1964 | |
| show more | ||
Data gaps
| type of concern | product conditions | reference |
| 16 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | PubMed |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| Cosmetic Ingredient Review Assessments | PPG-12-BUTETH-16 | •May contain harmful impurities |
| FDA Everything Added to Food | ALPHA-BUTYL-OMEGA-HYDROXYPOLY(OXYETHYLENE) POLY(OXYPROPYLENE) | • Although listed as a added to food, there is no current reported use of the substance, and, therefore, although toxicology information may be available in PAFA, it is not being updated. |
| Environment Canada Domestic Substance List | OXIRANE, METHYL-, POLYMER WITH OXIRANE, MONOBUTYL ETHER | •This chemical was deemed a moderate human health priority and was flagged by CEPA for further attention. |
| IFRA Fragrance Ingredient List | OXIRANE, METHYL-, POLYMER WITH OXIRANE, MONOBUTYL ETHER | •The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008. |
| RTECS®- Toxicology and Applied Pharmacology 1970 | PPG-12 BUTETH-16 | • broad systemic - Broad systemic toxicity (rat LD50) |
| RTECS®- Toxicology and Applied Pharmacology 1970 | PPG-12 BUTETH-16 | • broad systemic - Broad systemic toxicity (rat LD50) |
| RTECS®- Union Carbide Data Sheet | PPG-12 BUTETH-16 | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Union Carbide Data Sheet 1968 | PPG-12 BUTETH-16 | • broad systemic - Broad systemic toxicity (rat LD50) • skin - Primary skin irritant (rabbit ) |
| RTECS®- Union Carbide Data Sheet 1968 | PPG-12 BUTETH-16 | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Union Carbide Data Sheet 1970 | PPG-12 BUTETH-16 | • sense organ - Primary eye irritant (rabbit ) • skin - Primary skin irritant (rabbit ) |
| RTECS®- Union Carbide Data Sheet 1973 | PPG-12 BUTETH-16 | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Union Carbide Data Sheet 1965 | PPG-12 BUTETH-16 | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Union Carbide Data Sheet 1965 | PPG-12 BUTETH-16 | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Union Carbide Data Sheet 1968 | PPG-12 BUTETH-16 | • broad systemic - Broad systemic toxicity (rat LD50) |
| RTECS®- Union Carbide Data Sheet 1968 | PPG-12 BUTETH-16 | • broad systemic - Broad systemic toxicity (rat LD50) • skin - Primary skin irritant (rabbit ) |
| RTECS®- Union Carbide Data Sheet 1970 | PPG-12 BUTETH-16 | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Union Carbide Data Sheet 1964 | PPG-12 BUTETH-16 | • skin - Primary skin irritant (rabbit ) |
references
| government/industry list/academic study | reference |
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
| Environment Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| IFRA Fragrance Ingredient List | IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
| RTECS®- Toxicology and Applied Pharmacology 1970 | RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 16,657,1970 |
| RTECS®- Toxicology and Applied Pharmacology 1970 | RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 17,498,1970 |
| RTECS®- Union Carbide Data Sheet | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) |
| RTECS®- Union Carbide Data Sheet 1968 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 10/29/1968 |
| RTECS®- Union Carbide Data Sheet 1968 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 12/12/1968 |
| RTECS®- Union Carbide Data Sheet 1970 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 3/10/1970 |
| RTECS®- Union Carbide Data Sheet 1973 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 3/20/1973 |
| RTECS®- Union Carbide Data Sheet 1965 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 3/30/1965 |
| RTECS®- Union Carbide Data Sheet 1965 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 4/12/1965 |
| RTECS®- Union Carbide Data Sheet 1968 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 4/17/1968 |
| RTECS®- Union Carbide Data Sheet 1968 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 5/17/1968 |
| RTECS®- Union Carbide Data Sheet 1970 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 7/6/1970 |
| RTECS®- Union Carbide Data Sheet 1964 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 9/22/1964 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
Copyright © 2010 by Environmental Working Group
All rights reserved.
Favorites basket
No items in basket.
Skin Deep User Tools BETA
Looking for a product report that we don't have in Skin Deep? Sign up to enter it into the Skin Deep database and leave product reviews.
SKIN DEEP NEEDS YOUR HELP
We always want Skin Deep to be free to the public, but delivering high-quality research costs time and money. Help by donating just the cost of a bar of soap or bottle of shampoo.
WANT TO KNOW MORE?
Stay informed with email updates on toxics in everyday products and how they can affect your health.
JOIN THE CAMPAIGN
Find out more about the Campaign for Safe Cosmetics.