PROPANE

Propellant  

Also listed as

DIMETHYLMETHANE; LIQUEFIED PETROLEUM GAS; LPG; N-PROPANE; PROPANE (ACGIH:OSHA) ; PROPYL HYDRIDE; R 290


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
noCancer
noDevelopmental/reproductive toxicity
noRestrictions & warnings
yes, moderateAllergies/immunotoxicity
noContamination concerns
noOther strong concerns for this ingredient:
Multiple, additive exposure sources
noOther moderate concerns for this ingredient:
Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
noLesser or emerging concerns for this ingredient:
Data gaps
 
See products containing PROPANE

About PROPANE: Propane is the hydrocarbon.

PROPANE has reported used in the following product types: styling mousse/foam (60); shaving cream (men's) (24); styling gel/lotion (20); hair spray (19); body spray (16); shaving cream (15); antiperspirant/deodorant (men's) (14); shampoo (12); antiperspirant/deodorant (12); anti-fungal treatment (10)


Allergies/immunotoxicity

type of concern product conditions reference
Human toxicant - strong evidence    Cosmetic Ingredient Review Assessments

Multiple, additive exposure sources

type of concern product conditions reference
Used in food or as an additive with limited or no toxicity information available   FDA Everything Added to Food
Designated as safe for general or specific, limited use in food   FDA Food Additive Status
Designated as safe for general or specific, limited use in food   Cosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Classified as expected to be toxic or harmful    Environment Canada Domestic Substance List
Classified as medium human health priority    Environment Canada Domestic Substance List
show more

Irritation (skin, eyes, or lungs)

type of concern product conditions reference
Human irritant - strong evidence products for use around the eyes, on the skin, or may be aerosolized (airborne)  Cosmetic Ingredient Review Assessments

Occupational hazards

type of concern product conditions reference
Allowed workplace exposures restricted to high doses    RTECS®- TLV/BEI,2005
show more

Data gaps

type of concern product conditions reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product   Cosmetic Ingredient Review Assessments
1,612 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Miscellaneous

type of concern product conditions reference
Occupational hazards related to handling   European Union - Classification & Labelling

Persistence and bioaccumulation

type of concern product conditions reference
Not suspected to be bioaccumulative    Environment Canada Domestic Substance List

Neurotoxicity

type of concern product conditions reference
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study    National Library of Medicine HazMap

Ecotoxicology

type of concern product conditions reference
Not suspected to be an environmental toxin    Environment Canada Domestic Substance List



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingPROPANE•Extremely flammable
•Extremely flammable
FDA Food Additive StatusPROPANE• miscellaneous
• GRAS (generally recognized as safe) - use in food presumed safe based either on a history of use before 1958 or on published scientific evidence; need not be approved by the FDA prior to use in food; most have not limit for use but must conform to good manufacturing practices; some GRAS substances have quantitative limit for use in foods; by definition under Sec 201(s) of FD&C Act, not food additives
• Food additive: must be in accordance with good manufacturing practices, or sufficient for purpose; or in quantity not greater than required - CFR184.1655
• Combustion product gas - CFR173.350
Cosmetic Ingredient Review AssessmentsPROPANE•Safe as used in cosmetics according to industry panel (Cosmetic Ingredient Review, CIR)
•Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product
•Lung sensitizer
•Sensitizer - can instigate immune system response that can include itching, burning, scaling, hives, and blistering of skin
•Irritation (eyes, skin, or lungs)
•GRAS (generally recognized as safe) - use in food presumed safe based either on a history of use before 1958 or on published scientific evidence; need not be approved by the FDA prior to use in food
FDA Everything Added to FoodPROPANE• There is no reported use of the substance and there is no toxicology information available in PAFA.
National Library of Medicine HazMapPROPANE•Neurotoxin: CNS Solvent Syndrome;
•PEL (OSHA) - Permissible exposure limit (OSHA): 1000 ppm;
•Other Poison: Simple Asphyxiant;
•TLV (ACGIH) - Threshold limit value (ACGIH): 1000 ppm;
•Flammability (NFPA) - NFPA flammability code: 0 = will not burn; 1 = must be preheated; 2 = high ambient temp required; 3 = may ignite at ambient temp; 4 = burn readily: 4: burns readily;
•IDLH (NIOSH) - Immediately Dangerous to Life or Health: 2100 ppm;
•Odor Threshold High - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 20005 ppm;
•Odor Threshold Low - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 12225 ppm;
•MAK - Maximum Allowable Concentration (Federal Republic of Germany): 1000 ppm;
Environment Canada Domestic Substance ListPROPANE•This chemical was deemed a moderate human health priority and was flagged by CEPA for further attention. The chemical was flagged for suspected persistence.
Association of Occupational and Environmental ClinicsPROPANE• o
RTECS®- TLV/BEI,2005PROPANE• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2007PROPANE• occupationally related - ACGIH TLV (human TWA)
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994PROPANE• occupationally related - OSHA PEL (Fed Cont) (human TWA)
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994PROPANE• occupationally related - OSHA PEL (Gen Indu) (human TWA)

references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
FDA Food Additive StatusFDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Cosmetic Ingredient Review AssessmentsCIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
RTECS®- TLV/BEI,2005RTECS®- TLV/BEI,2005
RTECS®- TLV/BEI,2007RTECS®- TLV/BEI,2007
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994RTECS®- OSHA PEL (Fed Cont): 41,50-204.50,1994
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994RTECS®- OSHA PEL (Gen Indu): 29,1910.1000,1994

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.

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