SODIUM CARBONATE PEROXIDE || Skin Deep: Cosmetic Safety Reviews

SODIUM CARBONATE PEROXIDE

Oxidizing Agent; DEODORANT; OXIDISING

SCORE

	1	low hazard
	87%	data gap
(why scores have changed)

Also listed as

CARBONIC ACID, DISODIUM SALT, COMPD. WITH HYDROGEN PEROXIDE; PEROXY SODIUM CARBONATE; SODIUM PERCARBONATE; COMPD. WITH HYDROGEN PEROXIDE CARBONIC ACID, DISODIUM SALT; DISODIUM SALT COMPD. WITH HYDROGEN PEROXIDE CARBONIC ACID; CARBONIC ACID DISODIUM SALT, COMPD. WITH HYDROGEN PEROXIDE (H2O2) (2:3) ; DISODIUM CARBONATE, COMPOUND WITH HYDROGEN PEROXIDE (2:3) ; DISODIUM CARBONATE, HYDROGEN PEROXIDE (2:3) ; FB SODIUM PERCARBONATE; OXYPER; PERDOX

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns
	Lesser or emerging concerns for this ingredient: Neurotoxicity, Organ system toxicity (non-reproductive), Data gaps
	See products containing SODIUM CARBONATE PEROXIDE

About SODIUM CARBONATE PEROXIDE: Sodium Carbonate Peroxide is the inorganic salt.

SODIUM CARBONATE PEROXIDE has reported used in the following product types: toothpaste (10); tooth whitening (6); mouthwash (1)

Neurotoxicity

type of concern

product conditions

reference

One or more animal studies show brain, nervous system, or behavioral effects at moderate doses

RTECS^®- Toksikologicheskii Vestnik 1994

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient)

products that may be aerosolized (airborne)

RTECS^®- Toksikologicheskii Vestnik 1994

Data gaps

type of concern	product conditions	reference
Not assessed for safety in cosmetics by industry panel
4 studies in PubMed science library may include information on the toxicity of this chemical see search results ->		PubMed

Ecotoxicology

type of concern	product conditions	reference
Not suspected to be an environmental toxin		Environment Canada Domestic Substance List

Persistence and bioaccumulation

type of concern	product conditions	reference
Not suspected to be bioaccumulative		Environment Canada Domestic Substance List

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
Environment Canada Domestic Substance List	CARBONIC ACID DISODIUM SALT, COMPD. WITH HYDROGEN PEROXIDE (H2O2) (2:3)	•This chemical was NOT flagged by CEPA for further attention. The chemical was flagged for suspected persistence.
RTECS^®- Toksikologicheskii Vestnik 1994	SODIUM CARBONATE PEROXIDE	• respiratory - Dyspnea (rat LD50) • brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (rat LD50)
RTECS^®- Toksikologicheskii Vestnik 1994	SODIUM CARBONATE PEROXIDE	• brain, nervous system, or behavioral effect - Ataxia (rat LD50) • sense organ - Conjunctive irritation (rabbit TDLo) • sense organ - Corneal damage (rabbit TDLo) • sense organ - Other (rabbit TDLo) • respiratory - Respiratory depression (rat LD50) • brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (rat LD50)

references

government/industry list/academic study	reference
Environment Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
RTECS^®- Toksikologicheskii Vestnik 1994	RTECS^®- Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown (3),46,1994
RTECS^®- Toksikologicheskii Vestnik 1994	RTECS^®- Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown (3),47,1994

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